{"id":1233,"date":"2023-05-24T12:57:57","date_gmt":"2023-05-24T16:57:57","guid":{"rendered":"https:\/\/faculty.northeastern.edu\/advance\/?p=1233"},"modified":"2023-05-24T12:57:57","modified_gmt":"2023-05-24T16:57:57","slug":"rouhanifard-receives-3-4m-nih-grant-to-discover-rna-modification-sites-using-pseudouridine-modified-mrna","status":"publish","type":"post","link":"https:\/\/faculty.northeastern.edu\/advance\/rouhanifard-receives-3-4m-nih-grant-to-discover-rna-modification-sites-using-pseudouridine-modified-mrna\/","title":{"rendered":"Rouhanifard Receives $3.4M NIH Grant to Discover RNA Modification Sites Using Pseudouridine Modified mRNA"},"content":{"rendered":"<p>BioE Assistant Professor Sara Rouhanifard was awarded a $3.4 million NIH R01 grant for \u201cSynthetic mRNA Control Set for Nanopore-Based Pseudouridine Modification Profiling in Human Transcriptomes.\u201d The research has the potential to vastly increase insight into the epitranscriptome\u2014changes in chemical modifications of RNA that can affect gene expression within cells\u2014which could help identify new therapeutic targets and lead to new classes of drugs.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-1234\" src=\"https:\/\/faculty.northeastern.edu\/wp-content\/uploads\/sites\/5\/2023\/05\/rouhanifard-s-rect-300x200.png\" alt=\"\" width=\"300\" height=\"200\" srcset=\"https:\/\/faculty.northeastern.edu\/advance\/wp-content\/uploads\/sites\/5\/2023\/05\/rouhanifard-s-rect-300x200.png 300w, https:\/\/faculty.northeastern.edu\/advance\/wp-content\/uploads\/sites\/5\/2023\/05\/rouhanifard-s-rect.png 600w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/p>\n<p><strong><a class=\"btn bg--red --lg\" href=\"https:\/\/coe.northeastern.edu\/news\/rouhanifard-receives-3-4m-nih-grant-to-discover-rna-modification-sites-using-pseudouridine-modified-mrna\/\">Read More<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>BioE Assistant Professor Sara Rouhanifard was awarded a $3.4 million NIH R01 grant for \u201cSynthetic mRNA Control Set for Nanopore-Based Pseudouridine Modification Profiling in Human Transcriptomes.\u201d The research has the potential to vastly increase insight into the epitranscriptome\u2014changes in chemical modifications of RNA that can affect gene expression within cells\u2014which could help identify new therapeutic &hellip; <a href=\"https:\/\/faculty.northeastern.edu\/advance\/rouhanifard-receives-3-4m-nih-grant-to-discover-rna-modification-sites-using-pseudouridine-modified-mrna\/\">Continued<\/a><\/p>\n","protected":false},"author":12,"featured_media":1234,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[16,24,10],"tags":[],"class_list":["post-1233","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-success","category-faculty"],"_links":{"self":[{"href":"https:\/\/faculty.northeastern.edu\/advance\/wp-json\/wp\/v2\/posts\/1233","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/faculty.northeastern.edu\/advance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/faculty.northeastern.edu\/advance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/faculty.northeastern.edu\/advance\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/faculty.northeastern.edu\/advance\/wp-json\/wp\/v2\/comments?post=1233"}],"version-history":[{"count":0,"href":"https:\/\/faculty.northeastern.edu\/advance\/wp-json\/wp\/v2\/posts\/1233\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/faculty.northeastern.edu\/advance\/wp-json\/wp\/v2\/media\/1234"}],"wp:attachment":[{"href":"https:\/\/faculty.northeastern.edu\/advance\/wp-json\/wp\/v2\/media?parent=1233"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/faculty.northeastern.edu\/advance\/wp-json\/wp\/v2\/categories?post=1233"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/faculty.northeastern.edu\/advance\/wp-json\/wp\/v2\/tags?post=1233"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}